

MetaXL offers two alternatives to the RE model:ġ) The IVhet model provides a quasi-likelihood based expansion of the confidence interval around the inverse variance weighted For these reasons it is seriously flawed and It also makes unjustifiable changes to study weights.

Statistical error and has a larger mean squared error (MSE) than even the fixed effects estimator. However the RE estimator, as explained in the MetaXL User Guide, underestimates the Heterogeneity is usually dealt withīy employing the random effects (RE) model. There are two main issues with meta-analysis: heterogeneity between studies, and publication bias.

It produces a weighted average of the included studies results. Meta-analysis is a statistical method to combine the results of epidemiological studies in order to increase power. Now version 5Īdds cumulative meta-analysis to this already rich list of features Version 2 the inverse variance heterogeneity (IVhet) model, version 3 introduced the Doi plot and LFK index for the detection of publication bias, version 4 added network meta-analysis. Version 1 introduced the quality effects (QE) model, MetaXL keeps pushing the envelope of innovation in meta-analysis.
